I'm a Formulator

Are you new to mixture design of experiments (DOE) and not sure where to begin? Stat-Ease offers training, articles, books, software, online tutorials, newsletters, FAQs and DOE Resources, consulting services, and technical support to get you started. Whether you want to solve a specific quality problem, create the perfect product, improve your process, find a cheaper but equally good solution, or validate your process and procedures, Stat-Ease can help.

Contact us with questions, suggestions, or comments. Call 612.378.9449 or e-mail us.

What is Mixture Design and What's In It for You? A Heads-Up from Stat-Ease Consultant Mark Anderson

“Early in my career as a chemical engineer working in process development, I discovered that many of the chemists in our research and development center—especially those most brilliant in their field—failed to appreciate the power of planned experimentation. Furthermore, they disliked the mathematical aspects of statistical analysis. To top off their design-of-experiment (DOE) phobia, these otherwise very capable chemists also dismissed predictive models based only on empirical data. Ironically, in the hands of subject matter experts like these elite chemists, the statistical methods of mixture design and analysis provide the means for rapidly converging on optimal compositions—the “sweet spot,” as I like to call it.

This experience inspired me to begin work on detailing design and analysis of mixture experiments in a new book that fills in a major gap remaining after publication of DOE Simplified and RSM Simplified. This new "how-to" book, Formulation Simplified, co-authored by Patrick Whitcomb and Martin Bezener, is based on the Stat-Ease workshop “Mixture Design for Optimal Formulations” developed primarily by Pat. Readers of our third book will learn how to handle many ingredients simultaneously—not just one at a time, as dictated for time immemorial by “the scientific method.” As they will see in example after example, one needn’t hold all else constant while changing only one thing. Instead, why not take advantage of the modern-day parallel processing schemes of mixture designs that provide multicomponent testing?

After some months of work, I’ve established the WIIFM, that is, the “what’s in it for me” that will encourage formulators to work through the more intense aspects of mixture design, response modeling, statistical analysis and numerical optimization. It’s taken me three chapters to do this—it’s a tough nut to crack! Pat, Martin and I are offering this material to you as A Primer on Mixture Design: What’s In It for Formulators?. Feel free to download it for your education on this powerful tool in the DOE kit. All I ask is that if you like what you see and become convinced that this primer will be valuable for your colleagues, please send them the link.”



The quickest and easiest way to learn design of experiments is to attend a 2-day workshop. The class most suited to beginners is "Experiment Design Made Easy." This computer-intensive workshop covers the practical aspects of DOE. You will learn all about simple, but powerful two-level factorial designs.

Stat-Ease offers workshops for beginning through advanced experimenters. For a schedule of upcoming classes and prices, click here. We offer both public and private on-site training. To register for a public workshop, go to our Workshop Registration page. For more information on training, visit our web site, e-mail the Workshop Coordinator, or call 612.746.2038.

For those of you who don't have the time or money to attend a live workshop, we offer a variety of online classes through the Stat-Ease Academy. The Stat-Ease Academy offers e-learning content on a variety of topics. Learn basic statistics and the fundamentals of DOE at your convenience. No traveling necessary! All courses are now available free of charge. Click here to learn more and sign up for a workshop today here.

We offer multiple student, multiple class, and academic discounts. Contact the Workshop Coordinator for details.


Stat-Ease offers a wealth of articles on DOE. If you would like to learn more about this subject, we recommend you begin with the articles below.

1. Trimming the FAT out of Experimental Methods—This article is a primer on DOE versus the traditional OFAT method of experimentation.

2. Trimming the FAT: Part II—This follow-up article offers a case study that illustrates how a two-level factorial DOE can reveal a breakthrough interaction.

3. Rethink Experiment Design—This is another article on DOE versus the traditional OFAT method.

4. Eight Keys to Successful DOE—Using DOE successfully depends on understanding eight fundamental concepts which are explained in this article.

5. Design of Experiments—A Primer—This article looks at some of the basic DOE concepts that are necessary for practitioners to understand.

Click here to go the Articles page and see all available DOE articles and case studies.


Visit the Stat-Ease bookstore for recommended books on DOE. To get you off to a good start we suggest:

Formulation Simplified Book

1. "DOE Simplified: Practical Tools for Effective Experimentation, 3rd Edition," by Anderson & Whitcomb—This updated introductory text covers all of the basic essentials and is filled with interesting anecdotes and sidebars that make it fun to read.

Bring the DOE Simplified, 3rd Edition book to life with it's companion e-learning experience, the DOE Simplified Launchpad. This completely narrated presentation of the first three chapters of the book includes hands-on exercises and is designed to bring you up to speed on the basics of the two-level factorial design.  For more information, click here.

2. RSM Simplified: Optimizing Processes Using Response Surface Methods for Design of Experiments, 2nd Edition, by Anderson & Whitcomb—This book is the next step in your DOE education. Its simple and fun approach is for those who desire knowledge on response surface methods, but dislike the academic nature of other books on the topic.

3. Formulation Simplified: Finding the Sweet Spot through Design and Analysis of Experiments with Mixtures, by Anderson, Whitcomb, & Bezener—Formulation Simplified deviates significantly from all other statistical texts on design of experiments (DOE) for mixtures by making these powerful methods easy to study and fun to read. The authors provide a rich array of insightful case studies that illustrate the essentials of mixture DOE. Real-world examples are offered as problems at the end of many chapters for those who are serious about trying these new tools on their own. 

Online Interactive Tour & Tutorials

If you have the software but need help learning how to use it, click on the Video Tutorials tab located here. You will also find it helpful to work through the software tutorials (see link below).

1. Design-Expert Tutorials—Become familiar with the Design-Expert's features and capabilities and work through the problems provided to deepen your understanding.

Newsletters, FAQs and DOE Resources

Use the search bar above for answers to your specific questions. You will find a wealth of information in Mark Anderson's bi-monthly e-mail newsletter, the DOE FAQ Alert. Sign up to receive the latest FAQ's, alerts to timely articles, free software updates, and interesting tidbits.

Check out our printed newsletter, the Stat-Teaser. In it you will find fun experiments, DOE articles, software and workshop news, and much more. To sign up for the printed edition, e-mail info@statease.com with your full name and address. Be sure and note that you are signing up for the Stat-Teaser. (North America only—all others should sign up for the "DOE FAQ Alert" to be notified when the latest Stat-Teaser is available for download.)

Stat-Ease offers a large collection of case studies and articles on DOE. Look for applications in your industry.

Consulting Services

Patrick Whitcomb Mark Anderson Shari Kraber Martin Bezener

Consultants from left to right are: Top Row—Pat Whitcomb, Mark Anderson, Shari Kraber, and Martin Bezener

Do you need statistical support, or have a project that requires design of experiments (DOE) but don't know where to begin? Whether you want to solve a specific quality problem, create the perfect product, improve your process, find a cheaper but equally good solution, or validate your process and procedures, Stat-Ease can help. For fast help, Stat-Ease offers e-mail/phone and on-site consulting services. Most problems are solved for less than $2750. If you don't have the time or resources to learn DOE yourself, contact us for quick and cost-effective help solving your problem.

Step 1—Call 612.378.9449 or e-mail stathelp@statease.com to discuss the problem so that we can determine whether or not DOE can help you.

Step 2—Issue a purchase order, typically for up to $2750, for consulting services. There are no upfront charges.

Step 3—Start the consulting process. We bill only for time used, when it is used.

E-mail us your problem and contact information to get started. Or, call us now at 612.378.9449.

Click here for more information.

Technical (Non-Statistical) Support

(If you have a question on how to best use our software, please proceed to information on Statistical Support or Consulting Services provided below.) Having problems with software installation, activation, or program usage? Stat-Ease offers free technical support to its annual network license users and those with current Annual Support & Maintenance (ASM) agreements. Contact us by phone or e-mail and include the name of your organization, along with the serial number of the Design-Expert software license you are using (found under Help, About).

Phone: 612.378.9449
E-mail: support@statease.com

Business hours: 8:00-4:30 Central Time