One Factor - Use this design option in the situation when you only have one numeric factor. You can specify the model to estimate and if you want center points included. You also have the option of adding categoric factors, but it may be better to switch to ab optimal design.
Miscellaneous - This area includes the 3-level factorial designs, as well as special case designs such as Hybrid (3 - 7 factors), Pentagonal, and Hexagonal (2 factors).
Blank Spreadsheet - This is an option for importing existing data into the software for analysis. Follow the instructions on the screen to create a blank spreadsheet with the factor levels properly coded for DOE analysis. Then copy and paste your data into the spreadsheet.