This is a signal-to-noise ratio. It compares the range of the predicted values at the design points to the average prediction error. Ratios greater than 4 indicate adequate model discrimination.
Where,
ˆY are the predictions at the run settings
pˆσ2 is the residual mean square from ANOVA table.
p is the number of terms in the model.
n is the number of runs in the design.