Stat-Ease Blog

Here's the latest Publication Roundup! In these monthly posts, we'll feature recent papers that cited Design-Expert® or Stat-Ease® 360 software. Please submit your paper to us if you haven't seen it featured yet!

Mark's comment: Make sure to check out article #10, where the authors deploy response surface methods (with lots of impressive 3D plots!) to produce an eco-friendly material for civil engineering. 

1. Application of Novel Biochar Derived from Experimental Sewage Sludge Gasification as an Adsorbent for Heavy Metals Removal
   Sustainability 2025, 17(3), 997
   Authors: Domagoj Nakić, Hana Posavčić, Katarina Licht, and Dražen Vouk
   
2. Azadirachta indica Fruit Mucilage Aided Mucoadhesive Microspheres of Acyclovir for Drug Entrapment and Mucoadhesive Time Assets with Design-Expert Software
   Indian Journal of Pharmaceutical Education and Research, 2025; 59(1s): s243-s255.
   Authors: Gorantla Naresh Babu, M Menaka and Hindustan Abdul Ahad
   
3. Optimizing Water Hyacinth Compost and Chicken Manure for Enhancing Spinach Growth An Eco Friendly Approach to Sustainable Agriculture
   Indian Journal of Natural Sciences, 2024, 15(87), 976-977
   Authors: Mahmuda Parveen, Sujit Ghosh
   
4. Enhancing the tensile strength and morphology of Sansevieria trifasciata Laurentii fibers using liquid smoke and microwave treatments: an RSM approach
   Scientific Reports 15, Article number: 4420 (2025)
   Authors: Muhammad Arsyad Suyuti, Djarot B. Darmadi, Winarto, Putu Hadi Setyarini
   
5. Optimization of Biodiesel Production from Tannery Industry Fleshing Wastes Using Response Surface Methodology
   SAE Technical Paper 2025-28-0115
   Authors: Kanthasamy P, Arul Mozhi Selvan, Shanmugam P
   
6. Efficiency comparison of natural coagulants (Cactus pads and Moringa seeds) for treating textile wastewater (in the case of Kombolcha textile industry)
   Heliyon Volume 11, Issue 4, 28 February 2025
   Authors: Getahun Demeke Worku, Shimeles Nigussie Abate
   
7. Physico-chemical Characterisation of Ultrasound Processed Finger Millet Malt
   Asian Journal of Dairy and Food Research 14 February 2025
   Authors: Almas Begum Adoni, Madhava Mondru, Kaliramesh Siliveru, Vishnuvardhan Sidlagatta, Sandeep Raja Donepudi, Swapna Motamarri
   
8. Preparation of Gluten Free Cookie using Chestnut and Foxnut Flour Blend: Composition Optimization Through Response Surface Methodology
   Asian Journal of Dairy and Food Research Volume 44 Issue 1 (February 2025) : 84-91
   Authors: Divya Singh Chauhan, Apoorva Behari Lal, Anto Pradeep Raja Charles, Amit Pratap Singh, Ashish Khare, Pranav Vashisht
   
9. Optimization of Biochar Production from Cassava Peels: An Application of Response Surface Methodology
   Archives of Advanced Engineering Science 1-9
   Authors: Timothy Adekanye, Abiodun Okunola, Adeolu Adediran, Afolabi Tokunbo Yemisi, Aisha Aderibigbe
   
10. Investigations on mechanical and stress strain characteristics of geopolymer concrete reinforced with glass fibers
    Scientific Reports volume 15, Article number: 6335 (2025)
    Authors: Thunuguntla Chaitanya Srikrishna, Venkatesh Noolu, B. Sudheer Kumar Reddy, George Uwadiegwu Alaneme, Ravella Durga Prasad & M. VishnuPriyan
    
11. Study on hydration mechanism and ratio optimization of slag powder modified high-water material
    Scientific Reports volume 15, Article number: 6175 (2025)
    Authors: Xiang Ma, Chenyang Liu, Liwei Zhai, Shengrong Xie, Chaowen Wu & Jian Yang
    
12. Extraction and purification of total flavonoids from Zanthoxylum planispinum Var. Dintanensis leaves and effect of altitude on total flavonoids content
    Scientific Reports volume 15, Article number: 7080 (2025)
    Authors: Jiyue Wang, Xianqi Huang, Zhenyu Chen, Nian Chen, Mingli Yang, Chenggang Liang, Yanghua Yu & Denghong Shi
    
13. Preparation and characterization of inorganic foam modified with nano-magnesium hydroxide for inhibiting coal spontaneous combustion
    Physics of Fluids 37, 022152 (2025)
    Authors: Jingxia Tang, Jiawen Cai, Shengqiang Yang, Zhaoyang Yu, Kexin Chen, Xincheng Hu
    
14. Experimental approach and assessment of Zr conversion coatings on Al alloy using response surface methodology
    Corrosion Science, Volume 249, 2025, 112824
    Authors: Ana Kraš, Davorin Kramar, Ingrid Milošev

Welcome to our first Publication Roundup! In these monthly posts, we'll feature recent papers that cited Design-Expert® or Stat-Ease® 360 software. Please submit your paper to us if you haven't seen it featured yet!

Mark's comment: make sure to check out publication #4 by researchers from GITAM School of Science in Hyderabad, India. They provide all the raw data, the ANOVAs, model graphs and, most importantly, enhancing the quality of medicines via multifactor design of experiments (DOE).

1. Innovative study on chalcopyrite flotation efficiency with xanthate and ester collectors blend using response surface methodology (B.B.D): towards sustainability
   Scientific Reports volume 15, Article number: 65 (2025)
   Authors: Imkong Rathi & Shravan Kumar
   
2. Fabrication and In Vivo Evaluation of In Situ pH-Sensitive Hydrogel of Sonidegib–Invasomes via Intratumoral Delivery for Basal Cell Skin Cancer Management
   Pharmaceuticals 2025, 18(1), 31
   Authors: Maha M. Ghalwash, Amr Gamal Fouad, Nada H. Mohammed, Marwa M. Nagib, Sherif Faysal Abdelfattah Khalil, Amany Belal, Samar F. Miski, Nisreen Khalid Aref Albezrah, Amani Elsayed, Ahmed H. E. Hassan, Eun Joo Roh, & Shaimaa El-Housiny
   
3. Formulation development and evaluation, in silico PBPK modeling and in vivo pharmacodynamic studies of clozapine matrix type transdermal patches
   Scientific Reports volume 15, Article number: 1204 (2025)
   Authors: Abdul Qadir, Syed Umer Jan, Muhammad Harris Shoaib, Muhammad Sikandar, Rabia Ismail Yousuf, Fatima Ramzan Ali, Fahad Siddiqui, Abdul Jabbar Magsi, Ghulam Mustafa, Muhammad Talha Saleem, Shafi Mohammad, Mohammad Younis & Muhammad Arsalan
   
4. Unique Research for Developing a Full Factorial Design Evaluated Liquid Chromatography Technique for Estimating Budesonide and Formoterol Fumarate Dihydrate in the Presence of Specified and Degradation Impurities in Dry Powder Inhalation
   Biomedical Chromatography: Volume 39, Issue 2, February 2025
   Authors: Lova Gani Raju Bandaru, Naresh Konduru, Leela Prasad Kowtharapu, Rambabu Gundla, Phani Raja Kanuparthy, Naresh Kumar Katari
   
5. Synergistic effects of fly ash and graphene oxide composites at high temperatures and prediction using ANN and RSM approach
   Scientific Reports volume 15, Article number: 1604 (2025)
   Authors: I. Ramana & N. Parthasarathi
   
6. Enhancement Strategy for Protocatechuic Acid Production Using Corynebacterium glutamicum with Focus on Continuous Fermentation Scale-Up and Cytotoxicity Management
   International Journal of Molecular Sciences 2025, 26(1), 396
   Authors: Jiwoon Chung, Wooshik Shin, Chulhwan Park, and Jaehoon Cho
   
7. An exploration of RSM, ANN, and ANFIS models for methylene blue dye adsorption using Oryza sativa straw biomass: a comparative approach
   Scientific Reports volume 15, Article number: 2979 (2025)
   Authors: Sheetal Kumari, Smriti Agarwal, Manish Kumar, Pinki Sharma, Ajay Kumar, Abeer Hashem, Nouf H. Alotaibi, Elsayed Fathi Abd-Allah & Manoj Chandra Garg
   
8. Manipulated Slow Release of Florfenicol Hydrogels for Effective Treatment of Anti-Intestinal Bacterial Infections
   International Journal of Nanomedicine, Volume 2025:20, Pages 541—555, 13 January 2025.
   Authors: Luo W, Zhang M, Jiang Y, Ma G, Liu J, Dawood AS, Xie S, Algharib SA
   
9. Preparation of slow-release fertilizer derived from rice husk silica, hydroxypropyl methylcellulose, polyvinyl alcohol and paper composite coated urea
   Heliyon, Volume 11, Issue 2, 30 January 2025
   Authors: Idayatu Dere, Daniel T. Gungula, Semiu A. Kareem, Fartisincha Peingurta Andrew, Abdullahi M. Saddiq, Vadlya T. Tame, Haruna M. Kefas, David O. Patrick, Japari I. Joseph
   
10. Elimination of Ni(II) from wastewater using metal-organic frameworks and activated algae encapsulated in chitosan/carboxymethyl cellulose hydrogel beads: Adsorption isotherm, kinetic, and optimizing via Box-Behnken design optimization
    International Journal of Biological Macromolecules, 21 January 2025, In Press, Journal Pre-proof
    Authors: Gamil A.A.M. Al-Hazmi, Nadia H. Elsayed, Jawza Sh. Alnawmasi, Khadra B. Alomari, Ali Hamzah Alessa, Shareefa Ahmed Alshareef, A.A. El-Bindary
    
11. QbD-Driven preparation, characterization, and pharmacokinetic investigation of daidzein-l oaded nano-cargos of hydroxyapatite
    Scientific Reports volume 15, Article number: 2967 (2025)
    Authors: Namrata Gautam, Debopriya Dutta, Saurabh Mittal, Perwez Alam, Nasr A. Emad, Mohamed H. Al-Sabri, Suraj Pal Verma & Sushama Talegaonkar
    
12. Lubricity potentials of Azadirachta indica (neem) oil and Cyperus esculentus (tiger nut) oil extracts and their blends in machining of mild steel material
    Heliyon, Volume 11, Issue 2, 30 January 2025
    Authors: Ignatius Echezona Ekengwu, Ikechukwu Geoffrey Okoli, Obiora Clement Okafor, Obiora Nnaemeka Ezenwa, Joseph Chikodili Ogu
    
13. Process Evaluation and Analysis of Variance of Rice Husk Gasification Using Aspen Plus and Design Expert Software
    Chemistry Africa (2025)
    Authors: Ernest Mbamalu Ezeh, Isah Yakub Mohammed, Epere Aworabhi, Yousif Abdalla